⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515388 | 0.93 | MAPT (0.56) | — | |
| Hydrochloric Acid SCHEMBL27448355 | 0.92 | MAPT (0.50) | — | |
| SCHEMBL9304385 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL8408162 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL3120677 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL515245 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL514190 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL9305406 | 0.91 | MAPT (0.59) | — | |
| SCHEMBL11287218 | 0.89 | ALDH1A1 (0.46) | — | |
| SCHEMBL11859532 | 0.89 | MAPT (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840923-A | Chiral cyclopentene derivatives and their preparation | CHIROSCIENCE LIMITED (GB) | 1998-11-24 | — | — | US | claimed |
| US-20250066379-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-02-27 | — | — | US | disclosed |
| CN-118922422-A | Antimalarial drugs | 默沙东有限责任公司 | 2024-11-08 | — | — | CN | disclosed |
| EP-4444722-A1 | ANTIMALARIAL AGENTS | Merck Sharp & Dohme LLC (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107356-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023102747-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
| CN-102369173-B | Method for producing high-purity terminal olefin compound | KURARAY CO | 2014-09-10 | — | — | CN | disclosed |
| WO-2014022752-A1 | MACROCYCLES AS PIM INHIBITORS | AMGEN INC. (US) | 2014-02-06 | — | — | WO | disclosed |
| EP-2415740-B1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1734061-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20040122192-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20020156207-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1186619-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | Mitsui Chemicals, Inc. (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-5840923-A | Chiral cyclopentene derivatives and their preparation | CHIROSCIENCE LIMITED (GB) | 1998-11-24 | — | — | US | disclosed |
| US-4948865-A | Terpolymer of carbon monoxide, olefin and functionally substituted olefin | SHELL OIL COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| US-4841020-A | Catalytic polymerization of carbon monoxide with functional substituted ethylenically unsaturated monomer | SHELL OIL COMPANY (US) | 1989-06-20 | — | — | US | disclosed |
| US-4039585-A | Hydroformylation process | UOP INC. (US) | 1977-08-02 | — | — | US | disclosed |