Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3B | O95264 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 5/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1841829 | 0.98 | HTR3B (0.46) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL5145383 | 0.94 | HTR3E (0.46) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL1840872 | 0.86 | MAPT (0.44) | — | |
| Hydrochloric Acid SCHEMBL1841684 | 0.84 | MAPT (0.42) | — | |
| Hydrochloric Acid SCHEMBL1840946 | 0.84 | MAPT (0.42) | — | |
| SCHEMBL13016586 | 0.84 | HPGD (0.44) | HTR1AHTR2C | |
| SCHEMBL1231205 | 0.82 | CYP3A4 (0.42) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL3856354 | 0.82 | MEN1 (0.45) | HTR3BHTR3AHTR3EHTR3DHTR3C | |
| SCHEMBL33631 | 0.82 | PIK3CA (0.53) | — | |
| SCHEMBL10118729 | 0.82 | HTR2C (0.40) | HTR3BHTR3AHTR3EHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| CN-112089633-A | Oxidation dyeing method | 莱雅公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-105339049-B | Oxidation dyeing process implementing a pretreatment based on a composition rich in fatty substances and on a metal catalyst | 莱雅公司 | 2020-03-20 | — | — | CN | disclosed |
| WO-2019063611-A1 | OXIDATION DYEING PROCESS USING A COUPLER AND A PEROXYGENATED SALT AS OXIDIZING AGENT | L'OREAL (FR) | 2019-04-04 | — | — | WO | disclosed |
| EP-2155152-B1 | COLOURING COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND EXHIBITING AN ACIDIC PH | OREAL (FR) | 2018-07-04 | — | — | EP | disclosed |
| EP-3010594-B1 | OXIDATION DYEING PROCESS IMPLEMENTING A PRETREATMENT BASED ON A COMPOSITION RICH IN FATTY SUBSTANCES AND ON METAL CATALYSTS | OREAL (FR) | 2018-05-02 | — | — | EP | disclosed |
| US-9872822-B2 | Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition | L'OREAL (FR) | 2018-01-23 | — | — | US | disclosed |
| US-9789040-B2 | Oxidation dyeing process using a composition rich in fatty substances which comprises metal catalysts and couplers | L'OREAL (FR) | 2017-10-17 | — | — | US | disclosed |
| US-9789039-B2 | Oxidation dyeing process implementing a pretreatment based on a composition rich in fatty substances and on metal catalysts | L'OREAL (FR) | 2017-10-17 | — | — | US | disclosed |
| WO-2017050994-A1 | DYE COMPOSITION USING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE PARTICULAR AMINOBENZENE COUPLER, PROCESSES AND DEVICE | L'OREAL (FR) | 2017-03-30 | — | — | WO | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| CN-1977794-A | Composition comprising at least one 3-amino-pyrazolopyridine derivatives | OREAL (FR) | 2007-06-13 | — | — | CN | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | KRT18, MARK1, MARK2 | HTR3B 834/4885HTR3A 551/4885HTR3E 1298/4885 |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | KRT18, MARK1, MARK2 | HTR3B 900/4885HTR3A 584/4885HTR3E 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.