SCHEMBL5145592

SCHEMBL5145592

CCCCCC[N]C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
FAAH O00519 3/20 0.47
SOAT1 P35610 2/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
KDM4E B2RXH2 2/20 0.42
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
PPARG P37231 6/20 0.41
PPARD Q03181 6/20 0.41
PPARA Q07869 6/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
GPR84 Q9NQS5 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619163 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL6549736 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL1820400 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL4671252 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL81151 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL76612 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL80554 1.00 MEN1 (0.54) MEN1KMT2AFAAHSOAT1TP53
SCHEMBL1268125 0.98
SCHEMBL1238478 0.90
SCHEMBL5047549 0.90 FAAH (0.63) MEN1KMT2AFAAHSOAT1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP claimed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US claimed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO claimed
US-11998610-B2 Conjugates and methods of using the same FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-04 US disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
EP-4151621-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-03-22 EP disclosed
CN-113754541-A Micromolecule inhibitor targeting EB virus nuclear antigen protein, preparation method and application thereof 深圳湾实验室 2021-12-07 CN disclosed
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP disclosed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US disclosed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO disclosed
US-7301029-B2 Bipyridine Derivatives FUJIFILM FINECHEMICALS CO., LTD. (JP) 2007-11-27 US disclosed
EP-0752615-A2 Method for hardening gelatin and silver halide photographic light sensitive materials employing the method KONICA CORPORATION (JP) 1997-01-08 EP disclosed
US-5571660-A Method for forming an image KONICA CORPORATION (JP) 1996-11-05 US disclosed
EP-0642055-A1 A method of forming an image KONICA CORPORATION (JP) 1995-03-08 EP disclosed
US-5279920-A Containing a hydrazide compound KONICA CORPORATION (JP) 1994-01-18 US disclosed
EP-0539925-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1993-05-05 EP disclosed
US-4897469-A Aniline series azo reactive dyes ortho- or para-substituted by vinyl sulfonyl reactive groups BASF AKTIENGESELLSCHAFT (DE) 1990-01-30 US disclosed
US-4873172-A STABLE DEVELOPER CONTAINING A HYDRAZINE DERIVATIVE AND A COMPOUND BASED ON A FJUSED 4H-1,2,4-TRIAZOLE RING FUJI PHOTO FILM CO., LTD. (JP) 1989-10-10 US disclosed
US-4738918-A IN PRESENCE OF COMPOUND CONTAINING 1,2,4-TRIAZOLE RING FUJI PHOTO FILM CO., LTD. (JP) 1988-04-19 US disclosed
US-4275148-A THIO SUBSTITUTED PYRAZOLINES AS MAGENTA COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML MEN1 763/4885KMT2A 854/4885FAAH 2966/4885
US-11998610-B2 Conjugates and methods of using the same CD47, CD44, CD74 MEN1 2346/4885KMT2A 3520/4885FAAH 2742/4885
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 MEN1 2346/4885KMT2A 3520/4885FAAH 2742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.