SCHEMBL5145604

SCHEMBL5145604

ClCc1ccccc1CSCc1ccccc1CCl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2C9 P11712 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 1/20 0.42
ACHE P22303 1/20 0.41
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.38
KMT2A Q03164 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
THRB P10828 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
IDO1 P14902 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3149248 0.86 CYP1A2 (0.38) CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6
SCHEMBL29350459 0.83 TSHR (0.50) CYP1A2ALDH1A1TSHRMAPK1KMT2A
SCHEMBL150237 0.83 TSHR (0.50) CYP1A2ALDH1A1TSHRMAPK1KMT2A
SCHEMBL3150559 0.80 ALDH1A1 (0.38) CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6
Ammonia Solution, Strong SCHEMBL29017600 0.80 TSHR (0.48) CYP1A2ALDH1A1TSHRMAPK1KMT2A
Ammonia Solution, Strong SCHEMBL30821298 0.80 TSHR (0.48) CYP1A2ALDH1A1TSHRMAPK1KMT2A
Hydrochloric Acid SCHEMBL9192215 0.80 TSHR (0.48) ALDH1A1TSHRKMT2AL3MBTL1IDO1
SCHEMBL3155788 0.77 ALDH1A1 (0.46) CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6
SCHEMBL19801292 0.77 CYP1A1 (0.35) CYP1A2ALDH1A1TSHRMAPK1KMT2A
SCHEMBL8550582 0.75 HSPA5 (0.46) CYP3A4ALDH1A1TSHRKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303863-B2 Silver halide emulsion and silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-20060188829-A1 Silver halide emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2006-08-24 US disclosed