SCHEMBL5145689

SCHEMBL5145689

CCC(CCc1cccc(C)c1C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.43
LMNA P02545 1/20 0.42
CA2 P00918 1/20 0.41
MAPK1 P28482 1/20 0.41
PTGES O14684 2/20 0.39
ALOX5 P09917 2/20 0.39
PPARA Q07869 1/20 0.39
CYP1A2 P05177 1/20 0.37
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
NR3C2 P08235 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
POLB P06746 1/20 0.35
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7382016 0.82 PPARG (0.48) PPARGLMNAPTGESALOX5PPARA
SCHEMBL4986368 0.81 PPARG (0.37) PPARGLMNAPTGESALOX5PPARA
SCHEMBL4987597 0.77 ESR1 (0.34) PPARGPTGESALOX5PPARAKDM4C
SCHEMBL28741273 0.77 MAPK1 (0.40) PPARGLMNACA2MAPK1PTGES
SCHEMBL4986561 0.76 PPARG (0.36) PPARGLMNAPTGESALOX5PPARA
Acetic Acid SCHEMBL6269761 0.76 CTBP2 (0.42) PPARGPPARAKDM4CESR1ESR2
SCHEMBL585398 0.76 CYP1A2 (0.59) PPARGCA2MAPK1PPARACYP1A2
Hydrogen Peroxide SCHEMBL28094650 0.75 ESR1 (0.46) MAPK1KDM4CESR1ESR2POLB
SCHEMBL9469381 0.75 TAAR1 (0.46) CYP1A2NR3C2MEN1KMT2A
Hydrochloric Acid SCHEMBL28284494 0.75 CYP1A2 (0.57) PPARGCA2MAPK1PPARACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150216182-A1 COMPOSITIONS AND METHODS OF THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES, INC. 2015-08-06 US disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed