Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597808 | 0.98 | — | — | |
| SCHEMBL17466438 | 0.84 | — | — | |
| Bromide SCHEMBL5434502 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9193826 | 0.72 | KMT2A (0.36) | HTT | |
| SCHEMBL599009 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5439119 | 0.70 | — | — | |
| SCHEMBL17699210 | 0.65 | — | — | |
| SCHEMBL17257568 | 0.65 | — | — | |
| SCHEMBL4058154 | 0.64 | — | — | |
| SCHEMBL1901335 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273953-B2 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20060069287-A1 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069287-A1 | Process for producing arylamine | TYR, AADAC, AOC2 | HTT 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.