SCHEMBL5145886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16146853	0.80	PDPK1 (0.41)	CDK2PDPK1GDADPP4ALDH1A1
	SCHEMBL533603	0.79	PDPK1 (0.44)	CDK2PDPK1GDADPP4ALDH1A1
	SCHEMBL532461	0.79	CDK2 (0.66)	CDK2PDPK1GDADPP4ALDH1A1
	SCHEMBL2997392	0.76	DPP4 (0.61)	CDK2PDPK1GDADPP4ALDH1A1
	SCHEMBL612211	0.76	GDA (0.41)	CDK2PDPK1GDADPP4ALDH1A1
	SCHEMBL29873925	0.76	PDPK1 (0.66)	CDK2PDPK1GDADPP4PNP
	SCHEMBL497199	0.76	PDPK1 (0.66)	CDK2PDPK1GDADPP4PNP
	SCHEMBL135690	0.76	CDK2 (1.00)	CDK2PDPK1GDADPP4MAP3K5
	SCHEMBL5935896	0.76	CDK2 (0.61)	CDK2PDPK1GDADPP4CSNK2A1
	SCHEMBL16146291	0.72	CDK2 (0.45)	CDK2PDPK1GDADPP4XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.