Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL540582 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL3683188 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL1321915 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL29697739 | 1.00 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL28318238 | 0.97 | FFAR3 (0.39) | FFAR3LCKFYNALDH1A1TDP1 | |
| Propionic Acid SCHEMBL30607252 | 0.92 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1TDP1 | |
| Bicarbonate SCHEMBL8777797 | 0.91 | FFAR3 (0.37) | FFAR3ALDH1A1TDP1HDAC1HDAC2 | |
| Acetone SCHEMBL11797675 | 0.91 | LMNA (0.38) | FFAR3ALDH1A1TDP1TSHRKDM4E | |
| Bicarbonate SCHEMBL1357297 | 0.91 | FFAR3 (0.37) | FFAR3ALDH1A1TDP1HDAC1HDAC2 | |
| Bicarbonate SCHEMBL31122181 | 0.91 | FFAR3 (0.37) | FFAR3ALDH1A1TDP1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276139-B2 | Method for concentrating solution | FUJIFILM CORPORATION (JP) | 2007-10-02 | — | — | US | disclosed |
| US-7252743-B2 | Method for concentrating solution | FUJIFILM CORPORATION (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20060144685-A1 | Method for concentrating solution | FUJI PHOTO FILM CO., LTD. | 2006-07-06 | — | — | US | disclosed |
| US-20050205131-A1 | Solution tank and method of storing solution | FUJI PHOTO FILM CO., LTD. | 2005-09-22 | — | — | US | disclosed |