Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.51 |
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3808002 | 0.98 | GSK3B (0.53) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL5146011 | 0.94 | GSK3B (0.51) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL8111016 | 0.86 | TOP2A (0.58) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL500863 | 0.85 | GSK3B (0.64) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL5868648 | 0.85 | GSK3B (0.60) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL3131876 | 0.84 | GSK3B (0.43) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL9377798 | 0.84 | MEN1 (0.56) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL1345439 | 0.83 | GSK3B (0.55) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL9089592 | 0.82 | TOP2A (0.55) | GSK3BTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL9374041 | 0.82 | GSK3B (0.49) | GSK3BTOP2ATOP2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304050-B2 | Antibacterial agents | PFIZER INC. (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1670793-A1 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050070523-A1 | Antibacterial agents | HAGEN SUSAN (US) | 2005-03-31 | — | — | US | disclosed |
| WO-2005026161-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070523-A1 | Antibacterial agents | MRPL21, ABCB11, NQO1 | GSK3B 3349/4885TOP2A 28/4885TOP2B 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.