SCHEMBL5146241

SCHEMBL5146241

C=CC(NCC(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ABCC4 O15439 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BLM P54132 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
PTGS2 P35354 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2782619 0.84 CTH (0.35) MAPTABCC4SLC6A2SLC6A4BLM
SCHEMBL6765365 0.77
SCHEMBL10676965 0.77 MAPT (0.35) MAPTABCC4SLC6A2SLC6A4BLM
SCHEMBL20999127 0.77
SCHEMBL12080476 0.77
SCHEMBL526331 0.74
SCHEMBL613872 0.74 MAPT (0.32) MAPTSLC6A2SLC6A4BLMSLC6A3
SCHEMBL1730363 0.74 MAPT (0.32) MAPTSLC6A2SLC6A4BLMSLC6A3
SCHEMBL1517802 0.74 MAPT (0.32) MAPTSLC6A2SLC6A4BLMSLC6A3
SCHEMBL467340 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660176-B2 Molecular imprinting of small particles, and production of small particles from solid state reactants VIRGINIA COMMONWEALTH UNIVERSITY 2003-12-09 US claimed
WO-2002059184-A2 MOLECULAR IMPRINTING OF SMALL PARTICLES, AND PRODUCTION OF SMALL PARTICLES FROM SOLID STATE REACTANTS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2002-08-01 WO claimed
US-20020102312-A1 Molecular imprinting of small particles, and production of small particles from solid state reactants VIRGINIA COMMONWEALTH UNIVERSITY 2002-08-01 US claimed
JP-11189786-A None JP disclosed
US-7442754-B2 Molecular imprinting of small particles, and production of small particles from solid state reactants VIRGINIA COMMONWEALTH UNIVERSITY (US) 2008-10-28 US disclosed
US-20080242820-A1 MOLECULAR IMPRINTING OF SMALL PARTICLES, AND PRODUCTION OF SMALL PARTICLES FROM SOLID STATE REACTANTS TEPPER GARY 2008-10-02 US disclosed
US-6660176-B2 Molecular imprinting of small particles, and production of small particles from solid state reactants VIRGINIA COMMONWEALTH UNIVERSITY 2003-12-09 US disclosed
WO-2002059184-A2 MOLECULAR IMPRINTING OF SMALL PARTICLES, AND PRODUCTION OF SMALL PARTICLES FROM SOLID STATE REACTANTS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2002-08-01 WO disclosed
US-20020102312-A1 Molecular imprinting of small particles, and production of small particles from solid state reactants VIRGINIA COMMONWEALTH UNIVERSITY 2002-08-01 US disclosed
JP-H11189786-A DETERGENT COMPOSITION KAO CORP 1999-07-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020102312-A1 Molecular imprinting of small particles, and production of small particles from solid state reactants MRPS22, MRPS27, EMG1 MAPT 697/4885ABCC4 4026/4885SLC6A2 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.