Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28296217 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL8576872 | 0.88 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL22253446 | 0.80 | TSHR (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL7534958 | 0.80 | TSHR (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL224653 | 0.80 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL100732 | 0.80 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL30320250 | 0.80 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL29700306 | 0.80 | ALDH1A1 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL14998080 | 0.80 | ALDH1A1 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL6414322 | 0.80 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590675-A1 | HETEROCYCLIC SIK INHIBITORS | Pfizer Inc. (US) | 2025-07-30 | — | — | EP | claimed |
| CN-119985443-A | Gold-silver alloy nano probe based on dual-signal cooperative detection, preparation method and application thereof | 延边大学 | 2025-05-13 | — | — | CN | claimed |
| CN-115448860-B | Synthesis method of o-methylthio benzonitrile | 上海海客宜家生物科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| WO-2024062360-A1 | HETEROCYCLIC SIK INHIBITORS | PFIZER INC. (US) | 2024-03-28 | — | — | WO | claimed |
| CN-116943590-B | Process for improving yield of 1, 2-benzisothiazolin-3-one | 安徽屹墩科技股份有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-116943590-A | Process for improving yield of 1, 2-benzisothiazolin-3-one | 安徽屹墩科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115872945-A | Synthesis method of N-methyl-1,2-benzisothiazolin-3-one | 联化科技（德州）有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115448860-A | Synthetic method of o-methylthiobenzonitrile | 上海海客宜家生物科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| WO-2022091014-A1 | INDUSTRIAL METHOD OF PRODUCING BENZISOTHIAZOLINONE | HIKAL LIMITED (IN) | 2022-05-05 | — | — | WO | claimed |
| CN-114044747-A | Synthetic method of o-methylthiobenzonitrile | 大连百傲化学股份有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-103145638-A | New preparation method of 2-butyl-1,2-benzoisothiazolin-3-ketone (BBIT) | SHANGHAI TIANLAN BIOTECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | claimed |
| EP-1081141-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 2005-05-04 | — | — | EP | claimed |
| EP-1377556-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | Pfizer Limited (GB) | 2004-01-07 | — | — | EP | claimed |
| WO-2002085860-A1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LIMITED (GB) | 2002-10-31 | — | — | WO | claimed |
| EP-1081141-A1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2001-03-07 | — | — | EP | claimed |
| CN-1061975-C | Cyanothiophenyl halide and process for producing the same | SUMITOMO SEIKA CHEMICALS (JP) | 2001-02-14 | — | — | CN | claimed |
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | claimed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | claimed |
| EP-0702008-A2 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-03-20 | — | — | EP | claimed |