SCHEMBL5146599

SCHEMBL5146599

OC[CH]C(O)C(O)C(O)CO

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 1/20 0.50
KDM4E B2RXH2 2/20 0.37
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680531 1.00 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6432653 0.82
SCHEMBL993214 0.74 LMNA (0.56) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL16747999 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL23497770 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL23113003 0.72 TDP1 (0.33) TDP1
SCHEMBL3089641 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylose SCHEMBL13279394 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL23497718 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylose SCHEMBL21114394 0.72 LMNA (0.53) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948125-B1 VOLUME ENHANCING HAIR CARE PREPARATION HENKEL AG & CO KGAA (DE) 2014-06-18 EP claimed
EP-1862198-A2 Brightening and/or dyeing agent with urea derivatives Henkel Kommanditgesellschaft auf Aktien (DE) 2007-12-05 EP claimed
US-20220390458-A1 FLUORESCENT PROBE AND APPLICATIONS THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-12-08 US disclosed
WO-2021058490-A2 FLUORESCENT PROBE AND APPLICATIONS THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2021-04-01 WO disclosed
EP-3795643-A1 FLUORESCENT PROBE AND APPLICATIONS THEREOF Centre National de la Recherche Scientifique (FR) 2021-03-24 EP disclosed
EP-2836188-B1 EMULSION HAVING UREA DERIVATIVES HENKEL AG & CO KGAA (DE) 2017-11-01 EP disclosed
EP-2633887-B1 Novel agent combination for efficient anti-wrinkle effect HENKEL AG&CO KGAA (DE) 2016-03-02 EP disclosed
EP-2878341-A2 Application of cosmetic compositions for the inactivation and/or elimination of skin mites Henkel AG & Co. KGaA (DE) 2015-06-03 EP disclosed
EP-2878292-A2 Application of cosmetic compositions for the inactivation and/or elimination of skin mites Henkel AG & Co. KGaA (DE) 2015-06-03 EP disclosed
EP-1948125-B1 VOLUME ENHANCING HAIR CARE PREPARATION HENKEL AG & CO KGAA (DE) 2014-06-18 EP disclosed
EP-2633887-A1 Novel agent combination for efficient anti-wrinkle effect Henkel AG&Co. KGAA (DE) 2013-09-04 EP disclosed
EP-2628479-A1 Cosmetic use of climbazol Henkel AG&Co. KGAA (DE) 2013-08-21 EP disclosed
EP-2601931-A2 Cosmetic use of 3-methyl-1-phenyl-5-pyrazolon Henkel AG&Co. KGAA (DE) 2013-06-12 EP disclosed
EP-2514401-A2 Cosmetic and dermatological compounds for dry skin Henkel AG & Co. KGaA (DE) 2012-10-24 EP disclosed
EP-1862198-A2 Brightening and/or dyeing agent with urea derivatives Henkel Kommanditgesellschaft auf Aktien (DE) 2007-12-05 EP disclosed
EP-0022504-B1 1-N-ALKYLSISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES BAYER AG (DE) 1983-03-16 EP disclosed
US-4335114-A 1-N-Alkylsisomicin derivatives, their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1982-06-15 US disclosed
EP-0022504-A1 1-N-alkylsisomicin derivatives, process for their preparation and their use as medicines BAYER AG (DE) 1981-01-21 EP disclosed