SCHEMBL5146804

SCHEMBL5146804

C=C(C(=O)O)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
NAPRT Q6XQN6 2/20 0.35
DAO P14920 1/20 0.35
TSHR P16473 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.33
AKT1 P31749 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
P4HTM Q9NXG6 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28545158 0.74 CES1 (0.41) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL17163820 0.74 CES1 (0.41) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL22200088 0.70 ESR1 (0.39) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL1130961 0.70 CES2 (0.48) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL6435768 0.68 CES1 (0.48) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL5144094 0.67 EGFR (0.39) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL29072538 0.66 CES2 (0.38) HPGDALDH1A1CES2CES1NAPRT
SCHEMBL28533098 0.65 CES1 (0.46) ALDH1A1CES1MAPTSMN1; SMN2ESR1
SCHEMBL10864802 0.65 CES2 (0.43) ALDH1A1CES2CES1TSHRMAPT
SCHEMBL10884957 0.64 HPGD (0.42) HPGDALDH1A1CES2CES1NAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 US claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP claimed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US claimed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US claimed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP claimed
EP-3875544-A1 PAINT SYSTEM WITH ANTI-FOULING PROPERTY Evonik Operations GmbH (DE) 2021-09-08 EP disclosed
EP-3271426-B1 PAINT SYSTEM CONTAINING ANTI-FOULING METAL OXIDE AND FUMED SILICA EVONIK DEGUSSA GMBH (DE) 2019-05-08 EP disclosed
EP-3271426-A1 PAINT SYSTEM CONTAINING ANTI-FOULING METAL OXIDE AND FUMED SILICA Evonik Degussa GmbH (DE) 2018-01-24 EP disclosed
WO-2016146484-A1 PAINT SYSTEM CONTAINING ANTI-FOULING METAL OXIDE AND FUMED SILICA EVONIK DEGUSSA GMBH (DE) 2016-09-22 WO disclosed