Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14712980 | 0.88 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL3221764 | 0.86 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL7037114 | 0.86 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL10935282 | 0.85 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4EHPGDLMNA | |
| SCHEMBL2950989 | 0.85 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL3224984 | 0.85 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL28559491 | 0.85 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL28370301 | 0.85 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL24525601 | 0.84 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL11420383 | 0.83 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1ALDH3A1ALDH1A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461028-A4 | TREATMENT FOR AGE-RELATED MACULAR DEGENERATION | UNIV CALIFORNIA (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1461028-A2 | TREATMENT FOR AGE-RELATED MACULAR DEGENERATION | The Regent of the University of California (US) | 2004-09-29 | — | — | EP | claimed |
| WO-2003049685-A2 | TREATMENT FOR AGE-RELATED MACULAR DEGENERATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-06-19 | — | — | WO | claimed |
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-1430362-A4 | PHOTOCONDUCTORS COMPRISING CYCLIC CARBONATE POLYMERS | LEXMARK INT INC (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1430362-A1 | PHOTOCONDUCTORS COMPRISING CYCLIC CARBONATE POLYMERS | Lexmark International, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2002099535-A1 | PHOTOCONDUCTORS COMPRISING CYCLIC CARBONATE POLYMERS | LEXMARK INTERNATIONAL, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-6489070-B1 | Photoconductors comprising cyclic carbonate polymers | LEXMARK INTERNATIONAL, INC. | 2002-12-03 | — | — | US | disclosed |
| US-5958929-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | SANOFI (FR) | 1999-09-28 | — | — | US | disclosed |
| US-5736548-A | CYCLIC GUANOSINE 3*,5*-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; TREATING HEART FAILURE, HYPERTENSION | SANOFI (FR) | 1998-04-07 | — | — | US | disclosed |
| US-4513142-A | Preparation of cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| US-4446321-A | COLOR FORMERS, CARBON-FREE DUPLICATION | STERLING DRUG INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4396767-A | COLORS, CARBONLESS DUPLICATION | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0074569-A2 | Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates | BAYER AG (DE) | 1983-03-23 | — | — | EP | disclosed |
| US-4363503-A | FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | disclosed |
| EP-0061128-A1 | Pyridine compounds, process for their preparation and systems containing them | STERLING DRUG INC. (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4015016-A | [(2-Alkoxyberzylidine)amino]quanidines and their anticoccidal use | THE DOW CHEMICAL COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
| US-3973039-A | [(2-Alkoxybenzylidine)amino]guanidines and their anticoccidial use | THE DOW CHEMICAL COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | DCLRE1A, AZI2, CHD9 | ALDH1A1 2376/4885L3MBTL1 2750/4885ALDH3A1 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.