Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 6/20 | 0.64 |
| ▸ | HTR1D | P28221 | 6/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.64 |
| ▸ | HTR1B | P28222 | 5/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HTR7 | P34969 | 3/20 | 0.64 |
| ▸ | HTR6 | P50406 | 3/20 | 0.64 |
| ▸ | HTR1E | P28566 | 2/20 | 0.64 |
| ▸ | HTR5A | P47898 | 2/20 | 0.64 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.64 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.64 |
| ▸ | HTR3B | O95264 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HTR1F | P30939 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075720 | 0.88 | KMT2A (0.72) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL5144423 | 0.84 | KMT2A (0.74) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL466333 | 0.84 | KMT2A (0.70) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL5227242 | 0.83 | KMT2A (0.69) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL28414663 | 0.83 | KMT2A (0.69) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL16058705 | 0.83 | KMT2A (0.69) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL5144364 | 0.83 | KMT2A (0.65) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL5085972 | 0.81 | KMT2A (0.65) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| SCHEMBL5085568 | 0.81 | KMT2A (0.65) | KMT2AHTR1AHTR1DMTNR1AHTR1B | |
| Mebufotenin SCHEMBL7205139 | 0.80 | KMT2A (1.00) | KMT2AHTR1AHTR1DMTNR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476152-A4 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | UNIV IOWA RES FOUND (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1476152-A2 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | University of Iowa Research Foundation (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003070177-A2 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2003-08-28 | — | — | WO | disclosed |