Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872612 | 0.76 | APOBEC3A (0.43) | APOBEC3AAPOBEC3GKDM4CDRD2DRD4 | |
| SCHEMBL24983902 | 0.73 | APOBEC3A (0.38) | APOBEC3AAPOBEC3G | |
| SCHEMBL21515669 | 0.69 | APOBEC3A (0.49) | APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL4800485 | 0.69 | APOBEC3A (0.51) | APOBEC3AAPOBEC3GKDM4ENPC1RAB9A | |
| SCHEMBL5147052 | 0.68 | CYP3A4 (0.45) | CYP3A4CYP2D6SOAT1TSHRSMPD1 | |
| SCHEMBL7453009 | 0.67 | SOAT1 (0.49) | CYP3A4CYP2D6SOAT1KDM4ETSHR | |
| SCHEMBL21494430 | 0.67 | SOAT1 (0.49) | CYP3A4CYP2D6SOAT1KDM4ETSHR | |
| SCHEMBL4885285 | 0.67 | SOAT1 (0.49) | CYP3A4CYP2D6SOAT1KDM4ETSHR | |
| SCHEMBL675902 | 0.67 | SOAT1 (0.49) | CYP3A4CYP2D6SOAT1KDM4ETSHR | |
| SCHEMBL3221935 | 0.67 | SOAT1 (0.49) | CYP3A4CYP2D6SOAT1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004157-A2 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AS WELL AS COMBINATION THERAPY RELATING THERETO | Arena Pharmaceuticals, Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120702-A2 | USE OF GPR119 RECEPTOR AGONISTS FOR INCREASING BONE MASS AND FOR TREATING OSTEOPOROSIS, AND COMBINATION THERAPY RELATING THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |