Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885285 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL29869794 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL7453009 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL28251708 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL675902 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL21494430 | 1.00 | SOAT1 (0.49) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL423447 | 0.98 | CYP2D6 (0.50) | SOAT1CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL29379587 | 0.92 | CYP2C19 (0.56) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL6803 | 0.92 | CYP2C19 (0.56) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL2271442 | 0.89 | TSHR (0.46) | SOAT1CYP3A4LMNAALOX12FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100055056-A1 | AGENT FOR IMPROVING PERMEATION OF A DRUG INTO A NAIL AND AN EXTERNAL TREATING AGENT CONTAINING THE SAME | SATO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1996003379-A1 | THE ALKOXYLATION OF HETEROCYCLIC COMPOUNDS IN THE PRESENCE OF FLUORINE | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100055056-A1 | AGENT FOR IMPROVING PERMEATION OF A DRUG INTO A NAIL AND AN EXTERNAL TREATING AGENT CONTAINING THE SAME | ETF1, POLR1C, NACA | SOAT1 1036/4885CYP2D6 429/4885CYP1A2 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.