Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 6/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 6/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515927 | 0.86 | TYR (0.42) | CYBBNOX4TYRTRIM24TRIM33 | |
| SCHEMBL11823877 | 0.86 | TYR (0.42) | CYBBNOX4TYRTRIM24TRIM33 | |
| SCHEMBL24991896 | 0.84 | CYBB (0.39) | CYBBNOX4L3MBTL1APPEGFR | |
| SCHEMBL5729223 | 0.83 | TYR (0.46) | TYRTRIM24TRIM33L3MBTL1ALDH1A1 | |
| SCHEMBL10844181 | 0.83 | TYR (0.47) | CYBBNOX4TYRTRIM24TRIM33 | |
| SCHEMBL24991908 | 0.83 | EGFR (0.44) | CYBBNOX4L3MBTL1APPEGFR | |
| SCHEMBL24991974 | 0.83 | CYBB (0.38) | CYBBNOX4L3MBTL1APPEGFR | |
| SCHEMBL11740869 | 0.82 | ALDH1A1 (0.42) | CYBBNOX4TYRTRIM24TRIM33 | |
| SCHEMBL26562502 | 0.81 | CYBB (0.40) | CYBBNOX4L3MBTL1APPEGFR | |
| SCHEMBL61553 | 0.81 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624900-A4 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | UNIV CALIFORNIA (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-03-08 | — | — | US | disclosed |
| EP-1624900-A2 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2005040337-A2 | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | APBA1, CLTB, FABP7 | CYBB 1885/4885NOX4 3718/4885TYR 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.