Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 7/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221297 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1TRAP1HSP90B1KCNH2 | |
| SCHEMBL5147169 | 0.84 | CDC7 (0.47) | HSP90AA1HSP90AB1TRAP1HSP90B1HDAC1 | |
| SCHEMBL15604108 | 0.84 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1TRAP1HSP90B1HDAC1 | |
| SCHEMBL1220590 | 0.79 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1TRAP1HSP90B1KDM4E | |
| SCHEMBL1219473 | 0.79 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1TRAP1HSP90B1HDAC1 | |
| SCHEMBL18103331 | 0.78 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1TRAP1HSP90B1KDM4E | |
| SCHEMBL1218886 | 0.77 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1TRAP1HSP90B1KDM4E | |
| SCHEMBL5148489 | 0.73 | HDAC1 (0.45) | HDAC1HDAC6KDM4EALDH1A1TP53 | |
| SCHEMBL4791645 | 0.72 | CDC7 (0.48) | KDM4E | |
| SCHEMBL12819736 | 0.70 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1TRAP1HSP90B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | claimed |
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2007035620-A2 | CARBAZOLE DERIVATIVES | SERENEX, INC. (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185184-A1 | Carbazole derivatives | CCNI, MKI67, CCNB3 | HSP90AA1 3066/4885HSP90AB1 2567/4885TRAP1 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.