Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824057 | 0.79 | GSK3B (0.32) | GSK3B | |
| SCHEMBL5543849 | 0.74 | GSK3B (0.35) | GSK3BDAO | |
| SCHEMBL3714951 | 0.74 | VCAM1 (0.38) | — | |
| SCHEMBL9768926 | 0.72 | — | — | |
| SCHEMBL10078226 | 0.70 | — | — | |
| SCHEMBL7368227 | 0.70 | — | — | |
| SCHEMBL5009882 | 0.70 | — | — | |
| SCHEMBL13857947 | 0.69 | HDAC3 (0.46) | — | |
| SCHEMBL10998017 | 0.68 | GSK3B (0.46) | GSK3BDAO | |
| SCHEMBL10582977 | 0.67 | MEN1 (0.49) | GSK3BDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831207-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066172-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2006-06-22 | — | — | WO | disclosed |