SCHEMBL5147451

SCHEMBL5147451

BrC(Br)(Br)C(Br)(Br)c1ccccc1.Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
HSPD1 P10809 1/20 0.42
HSPE1 P61604 1/20 0.42
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
AKR1C4 P17516 2/20 0.41
AKR1C3 P42330 2/20 0.41
AKR1C2 P52895 2/20 0.41
AKR1C1 Q04828 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL756427 0.76 KCNN4 (0.46) CYP3A4TSHRTDP1ALOX15ALDH1A1
SCHEMBL8673233 0.74 CRHBP (0.54) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL5990792 0.74 CRHBP (0.54) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL18224 0.73 CYP3A4 (1.00) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL5596946 0.73 CYP3A4 (0.43) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL10546483 0.71 CYP3A4 (0.93) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL11020186 0.71 CYP3A4 (0.93) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL29858952 0.71 CYP3A4 (0.93) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL28015082 0.71 CYP3A4 (0.93) CYP3A4TSHRTDP1CRHBPCRHR2
SCHEMBL4340169 0.71 CYP3A4 (0.93) CYP3A4TSHRTDP1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3936556-B1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-21 EP claimed
CN-110291137-B Moisture-cured flame-retardant wire and cable constructions with improved glancing impact properties 陶氏环球技术有限责任公司 2023-04-25 CN claimed
US-11339292-B2 Flame-retardant, moisture-cured wire and cable constructions with improved glancing impact performance DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-24 US claimed
EP-3936556-A1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE Dow Global Technologies Llc (US) 2022-01-12 EP claimed
EP-3589681-B1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2021-12-01 EP claimed
US-20200207972-A1 MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS DOW GLOBAL TECHNOLOGIES LLC 2020-07-02 US claimed
EP-3646349-A1 MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS Dow Global Technologies LLC (US) 2020-05-06 EP claimed
CN-110770853-A Moisture cured wire and cable constructions 陶氏环球技术有限责任公司 2020-02-07 CN claimed
WO-2019005439-A1 MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-01-03 WO claimed
WO-2018160846-A1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-07 WO claimed
EP-3535312-B1 SEMI-CRYSTALLINE POLYOLEFIN-BASED ADDITIVE MASTERBATCH COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-21 EP disclosed
EP-3661721-B1 MOISTURE CURABLE COMPOSITION FOR WIRE AND CABLE INSULATION AND JACKET LAYERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-04 EP disclosed
EP-3936556-B1 FLAME-RETARDANT, MOISTURE-CURED WIRE AND CABLE CONSTRUCTIONS WITH IMPROVED GLANCING IMPACT PERFORMANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-21 EP disclosed
CN-110291137-B Moisture-cured flame-retardant wire and cable constructions with improved glancing impact properties 陶氏环球技术有限责任公司 2023-04-25 CN disclosed
EP-4023713-A1 COMPOSITIONS COMPRISING BROMINATED POLYMERIC FLAME RETARDANT Dow Global Technologies LLC (US) 2022-07-06 EP disclosed
US-6936655-B2 Crosslinkable flame retardant wire and cable compositions having improved abrasion resistance EQUISTAR CHEMICALS, LP (US) 2005-08-30 US disclosed
US-20050049343-A1 Crosslinkable flame retardant wire and cable compositions having improved abrasion resistance EQUISTAR CHEMICALS, LP 2005-03-03 US disclosed
US-6392153-B1 WEAR AND OXIDATION RESISTANCE; FIREPROOFING EQUISTAR CHEMICALS, LP 2002-05-21 US disclosed
WO-2000036613-A1 ELECTRICAL CONDUCTIVE ASSEMBLY EQUISTAR CHEMICALS, LP (US) 2000-06-22 WO disclosed
US-5439965-A Copolymer of ethylene and aliphatic vinyl ester containing a carbocyclic chloro- or bromohydrocarbon, antimony trioxide, and an organic peroxide; flame resistant; for wire and cable QUANTUM CHEMICAL CORPORATION (US) 1995-08-08 US disclosed