SCHEMBL5147799

SCHEMBL5147799

CC(C)(C)CC(C)(C)Oc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.36
KDM4E B2RXH2 3/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 3/20 0.34
IGF2BP2 Q9Y6M1 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8857110 0.90 NPC1 (0.43) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL6930005 0.85 NPC1 (0.54) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL5147792 0.83 NPC1 (0.48) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL6924417 0.83 NPC1 (0.37) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL15508 0.80 NPC1 (0.56) NPC1RAB9ALMNAKDM4EPPARG
Octrizole SCHEMBL29349945 0.80 NPC1 (0.56) NPC1RAB9ALMNAKDM4EPPARG
Octrizole SCHEMBL28983126 0.80 NPC1 (0.56) NPC1RAB9ALMNAKDM4EPPARG
Octrizole SCHEMBL30315837 0.79 NPC1 (0.55) NPC1RAB9ALMNAKDM4EPPARG
SCHEMBL29768260 0.78 RAB9A (0.64) NPC1RAB9ALMNAHTTKDM4E
SCHEMBL563559 0.78 RAB9A (0.64) NPC1RAB9ALMNAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117701101-A Weather-resistant water-based epoxy resin coating and preparation method thereof 南通大学 2024-03-15 CN claimed
CN-117624812-A Ultraviolet aging resistant polymer-based composite material and preparation method thereof 中国科学院化学研究所 2024-03-01 CN claimed
CN-115353814-A Heat-insulating and sound-insulating glass laminating adhesive and preparation method thereof 浙江祥邦科技股份有限公司 2022-11-18 CN claimed
CN-117701101-A Weather-resistant water-based epoxy resin coating and preparation method thereof 南通大学 2024-03-15 CN disclosed
CN-115353814-A Heat-insulating and sound-insulating glass laminating adhesive and preparation method thereof 浙江祥邦科技股份有限公司 2022-11-18 CN disclosed
EP-0641030-B1 Photoelectric conversion device and photoelectric conversion module each having a protective member comprised of fluorine-containing polymer resin CANON KK (JP) 2007-01-03 EP disclosed
US-5530264-A CONTAINING A TRANSPARENT, CROSSLINKED FLUOROPOLYMER CANON KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed
EP-0641030-A2 Photoelectric conversion device and photoelectric conversion module each having a protective member comprised of fluorine-containing polymer resin CANON KABUSHIKI KAISHA (JP) 1995-03-01 EP disclosed