SCHEMBL5147906

SCHEMBL5147906

NC(=O)c1ccncc1CCO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.49
SIRT3 Q9NTG7 2/20 0.49
KDM4C Q9H3R0 6/20 0.42
KDM4E B2RXH2 4/20 0.42
KDM6B O15054 3/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4A O75164 2/20 0.42
KDM4D Q6B0I6 2/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 1/20 0.41
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
SARM1 Q6SZW1 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29923810 0.86 TDP1 (0.49) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL18421593 0.85 TDP1 (0.52) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL30990566 0.84 TDP1 (0.51) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL8594489 0.81 TDP1 (0.56) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL3634352 0.81 TDP1 (0.49) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL17673040 0.80 KDM4C (0.50) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL27804148 0.80 TDP1 (0.47) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL25181398 0.80 TDP1 (0.50) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL22732059 0.80 GPBAR1 (0.44) TDP1SIRT3KDM4CKDM4EKDM6B
SCHEMBL509800 0.79 TDP1 (0.46) TDP1SIRT3KDM4CKDM4EKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110512308-B Linear bicomponent filaments, fibres or tapes 纳米及先进材料研发院有限公司 2022-03-22 CN claimed
EP-1347784-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION Bristol-Myers Squibb Pharma Company (US) 2003-10-01 EP claimed
WO-2002036173-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-05-10 WO claimed
JP-2001525796-A 2001-12-11 JP claimed
EP-0999856-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION Du Pont Pharmaceuticals Company (US) 2000-05-17 EP claimed
WO-1998015295-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION DUPONT PHARMACEUTICALS COMPANY (US) 1998-04-16 WO claimed
CN-110512308-B Linear bicomponent filaments, fibres or tapes 纳米及先进材料研发院有限公司 2022-03-22 CN disclosed
CN-102691118-B Preparation method of shape memory hollow fiber UNIV HONG KONG POLYTECHNIC 2015-02-25 CN disclosed
CN-102691118-A Preparation method of shape memory hollow fiber UNIV HONG KONG POLYTECHNIC 2012-09-26 CN disclosed
US-20070072096-A1 Negative curable dye-containing composition, color filter, and method of manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
WO-2003099810-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2003-12-04 WO disclosed
EP-1347784-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION Bristol-Myers Squibb Pharma Company (US) 2003-10-01 EP disclosed
EP-0999856-B1 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION BRISTOL MYERS SQUIBB PHARMA CO (US) 2003-05-14 EP disclosed
EP-1293214-A2 LTB4 antagonists and radiopharmaceuticals for imaging infection and inflammation Bristol-Myers Squibb Pharma Company (US) 2003-03-19 EP disclosed
US-6416733-B1 RADIOPHARMACEUTICALS BIND IN VIVO TO THE LEUKOTRIENE B4 (LTB4) RECEPTOR ON THE SURFACE OF LEUKOCYTES WHICH ACCUMULATE AT THE SITE OF INFECTION AND INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-07-09 US disclosed
WO-2002036173-A2 SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-05-10 WO disclosed
EP-0999856-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION Du Pont Pharmaceuticals Company (US) 2000-05-17 EP disclosed
WO-1998015295-A2 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION DUPONT PHARMACEUTICALS COMPANY (US) 1998-04-16 WO disclosed