SCHEMBL509800

SCHEMBL509800

C[Si](C)(C)CCCc1cnccc1C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
SIRT3 Q9NTG7 1/20 0.46
KDM4C Q9H3R0 14/20 0.40
KDM6B O15054 6/20 0.40
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4A O75164 2/20 0.40
KDM4D Q6B0I6 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
TSHR P16473 1/20 0.35
MC4R P32245 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634352 0.84 TDP1 (0.49) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL27804148 0.83 TDP1 (0.47) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL30990566 0.81 TDP1 (0.51) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL29923810 0.79 TDP1 (0.49) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL5147906 0.79 TDP1 (0.49) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL8594489 0.79 TDP1 (0.56) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL18421593 0.75 TDP1 (0.52) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL28038877 0.74 TDP1 (0.51) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL17673040 0.74 KDM4C (0.50) TDP1SIRT3KDM4CKDM6BKDM4E
SCHEMBL25181398 0.74 TDP1 (0.50) TDP1SIRT3KDM4CKDM6BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130107183-A1 LIQUID CRYSTAL DISPLAY DEVICE HAVING ORGANIC ALIGNMENT LAYER AND FABRICATION METHOD THEREOF LG DISPLAY CO., LTD. (KR) 2013-05-02 US disclosed
US-8345200-B2 Liquid crystal display device having organic alignment layer and fabrication method thereof LG DISPLAY CO., LTD. (KR) 2013-01-01 US disclosed
US-20120026441-A1 LIQUID CRYSTAL DISPLAY DEVICE HAVING ORGANIC ALIGNMENT LAYER AND FABRICATION METHOD THEREOF CHAE GEE-SUNG (KR) 2012-02-02 US disclosed
US-8039063-B2 Liquid crystal display device having organic alignment layer and fabrication method thereof LG DISPLAY CO., LTD. (KR) 2011-10-18 US disclosed
US-20100260937-A1 LIQUID CRYSTAL DISPLAY DEVICE HAVING ORGANIC ALIGNMENT LAYER AND FABRICATION METHOD THEREOF LG DISPLAY CO., LTD. 2010-10-14 US disclosed
US-7755731-B2 Liquid crystal display device having organic alignment layer and fabrication method thereof LG DISPLAY CO., LTD. (KR) 2010-07-13 US disclosed
US-20070154655-A1 Liquid crystal display device having organic alignment layer and fabrication method thereof LG.PHILIPS LCD CO., LTD. (KR) 2007-07-05 US disclosed