Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799921 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL5560856 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL9657559 | 0.75 | PPM1B (0.37) | LMNA | |
| SCHEMBL9175228 | 0.72 | MAPK1 (0.33) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL5415224 | 0.71 | PPP5C (0.31) | — | |
| SCHEMBL9989927 | 0.69 | PDE4D (0.30) | — | |
| SCHEMBL11866220 | 0.69 | MAPK1 (0.39) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL4601279 | 0.69 | MAPK1 (0.39) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL11866663 | 0.68 | NPSR1 (0.35) | NPSR1 | |
| SCHEMBL12988135 | 0.67 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476504-B1 | THERMOPLACTIC RESIN COMPOSITION AND METHOD 0F IMPROVING APPEARANCE | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-07-03 | — | — | EP | disclosed |
| US-7214732-B2 | Thermoplastic resin composition and method of improving appearance | GENERAL ELECTRIC COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-20030162871-A1 | Thermoplastic resin composition and method of improving appearance | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2003-08-28 | — | — | US | disclosed |