⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812717 | 0.81 | ALDH1A1 (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL16781743 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL2187016 | 0.75 | PDE7A (0.35) | — | |
| SCHEMBL5890646 | 0.73 | KDM4E (0.52) | — | |
| SCHEMBL28443362 | 0.73 | POLB (0.41) | — | |
| SCHEMBL11586245 | 0.73 | — | — | |
| SCHEMBL2986829 | 0.73 | KMT2A (0.46) | — | |
| SCHEMBL31087243 | 0.73 | KDM4E (0.52) | — | |
| SCHEMBL199800 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL21830229 | 0.72 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | claimed |
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | claimed |
| EP-1856060-A1 | SUBSTITUTED 1,1,1-TRIFLUORO-3-[(BENZYL)-(PYRIMIDIN-2-YL)-AMINO]-PROP AN-2-OL COMPOUNDS | Pfizer Products Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006090250-A1 | SUBSTITUTED 1,1,1-TRIFLUORO-3-[(BENZYL)-(PYRIMIDIN-2-YL)-AMINO]-PROP AN-2-OL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2006-08-31 | — | — | WO | claimed |
| EP-1465869-A4 | MODULATORS OF LXR | X CEPTOR THERAPEUTICS INC (US) | 2005-12-28 | — | — | EP | claimed |
| JP-2005536450-A | — | — | 2005-12-02 | — | — | JP | claimed |
| EP-1465869-A1 | MODULATORS OF LXR | X-Ceptor Therapeutics, Inc. (US) | 2004-10-13 | — | — | EP | claimed |
| US-20030181420-A1 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS, INC. | 2003-09-25 | — | — | US | claimed |
| WO-2003059884-A1 | MODULATORS OF LXR | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| EP-1192178-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000078795-A2 | RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1) | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| WO-2023190836-A1 | ADDITIVE FOR RESIN, METHOD FOR PRODUCING SAME, AND METHOD FOR SUPPRESSING COLORATION OF RESIN | ミヨシ油脂株式会社 | 2023-10-05 | — | — | WO | disclosed |
| US-11739171-B2 | Method for producing α-olefin/(meth)acrylic acid ester copolymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2023-08-29 | — | — | US | disclosed |
| CN-111971310-B | Process for producing alpha-olefin/(meth) acrylate copolymer | 日本聚乙烯株式会社 | 2023-07-18 | — | — | CN | disclosed |
| US-5192783-A | Fungicides for plants | ROHM AND HAAS COMPANY (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0344110-B1 | SUBSTITUTED NAPHTHACENES-5,12-DIONES AND THEIR USE | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5001243-A | Substituted naphthacene-5, 12-diones | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0344110-A2 | Substituted naphthacenes-5,12-diones and their use | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| CN-86108961-A | 1-CARBACEPHALOSPORIN ANTIBIOTICS | — | 1987-08-05 | — | — | CN | disclosed |