⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886 | 0.81 | APP (0.35) | — | |
| SCHEMBL4968126 | 0.79 | CYP3A4 (0.58) | — | |
| Hydrochloric Acid SCHEMBL9124177 | 0.78 | CYP3A4 (0.33) | — | |
| SCHEMBL8710625 | 0.77 | — | — | |
| SCHEMBL1070719 | 0.76 | MAPT (0.35) | — | |
| SCHEMBL14154506 | 0.75 | — | — | |
| SCHEMBL9611202 | 0.75 | FFAR1 (0.59) | — | |
| SCHEMBL2017650 | 0.75 | — | — | |
| SCHEMBL107461 | 0.75 | — | — | |
| SCHEMBL71478 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389009-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GFB (ABC), LLC | 2022-12-08 | — | — | US | claimed |
| CN-114761000-A | Substituted 1, 6-naphthyridine inhibitors of CDK5 | 金翅雀生物公司 | 2022-07-15 | — | — | CN | claimed |
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | claimed |
| WO-2021067569-A1 | SUBSTITUTED 1, 6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2021-04-08 | — | — | WO | claimed |
| CN-109679095-A | High-temperature-resistant polyamide-polyetherimide toughened polymer and preparation method thereof | 苏州予信天材新材料应用技术有限公司 | 2019-04-26 | — | — | CN | claimed |
| EP-1817336-B1 | AURISTATINS HAVING AN AMINOBENZOIC ACID UNIT AT THE N TERMINUS | SEATTLE GENETICS INC (US) | 2019-01-09 | — | — | EP | claimed |
| CN-105949508-B | A kind of heat stabilizer for PVC and its preparation method and application | 中国林业科学研究院林产化学工业研究所 | 2018-09-04 | — | — | CN | claimed |
| CN-102531875-B | 3-Oxo-1,2-naphthoquinone analogues, preparation method and application thereof | ZHENGZHOU UNIVERSITY (CN) | 2014-10-22 | — | — | CN | claimed |
| CN-103108869-A | Process for preparing aminobenzoylbenzofuran derivatives | SANOFI SA | 2013-05-15 | — | — | CN | claimed |
| CN-102531875-A | 3-Oxo-1,2-naphthoquinone analogues, preparation method and application thereof | UNIV ZHENGZHOU | 2012-07-04 | — | — | CN | claimed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | claimed |
| WO-1998002741-A9 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | — | 1998-05-22 | — | — | WO | claimed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | claimed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | claimed |
| WO-1997007131-A1 | ACYLATED OLIGOPEPTIDES CONTAINING PHOSPHOTYROSINE AS INHIBITORS OF PROTEIN TYROSINE KINASES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | claimed |
| EP-0505680-B1 | Octapeptide or heptapeptide derivatives, a process for preparing them as well as medicaments containing these compounds and the use of them | BIOSIGNAL KUTATO FEJLESZTOE (HU) | 1995-04-26 | — | — | EP | claimed |
| EP-0505680-A1 | Octapeptide or heptapeptide derivatives, a process for preparing them as well as medicaments containing these compounds and the use of them | BIOSIGNAL Kutato-Fejleszto Kft. (HU) | 1992-09-30 | — | — | EP | claimed |
| EP-0207894-B1 | HERBICIDALLY ACTIVE DERIVATIVES OF N-PHENYL-3,4,5,6-TETRAHYDROPHTHALIMIDE | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| EP-0233151-B1 | ESTERS AS HERBICIDES | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | claimed |
| US-4659569-A | Process for the production of virus vaccine | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1987-04-21 | — | — | US | claimed |