SCHEMBL1070719

SCHEMBL1070719

O=[C]c1ccc([C]=O)cc1.O=[C]c1cccc([C]=O)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 1/20 0.32
APP P05067 1/20 0.32
CA12 O43570 5/20 0.31
CA1 P00915 5/20 0.31
CA2 P00918 5/20 0.31
CA9 Q16790 5/20 0.31
CA14 Q9ULX7 1/20 0.31
FFAR1 O14842 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886 0.94 APP (0.35) MAPTMEN1ALDH1A1KMT2ACYP3A4
Hydrochloric Acid SCHEMBL9124177 0.91 CYP3A4 (0.33) MAPTMEN1ALDH1A1KMT2ACYP3A4
SCHEMBL98479 0.81 ENPP2 (0.48) MAPTMEN1ALDH1A1KMT2AFFAR1
SCHEMBL1666197 0.81 CA12 (0.50) MEN1KMT2ACA12CA1CA2
SCHEMBL104811 0.80 APP (0.32) APP
SCHEMBL7057192 0.79 APP (0.57) MAPTAPPCA12CA1CA2
SCHEMBL813 0.78
SCHEMBL7050853 0.78 ALDH1A1 (0.41) ALDH1A1CYP3A4FFAR1
SCHEMBL1070722 0.76 CES2 (0.46)
SCHEMBL11594853 0.76 ALDH1A1 (0.39) MEN1ALDH1A1KMT2ACYP3A4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026150-A1 POLYETHER KETONE KETONE AND A PROCESS FOR PREPARATION THEREOF GHARDA CHEMICALS LIMITED (IN) 2023-01-26 US disclosed
WO-2021105784-A1 POLYETHER KETONE KETONE AND A PROCESS FOR PREPARATION THEREOF GHARDA CHEMICALS LIMITED (IN) 2021-06-03 WO disclosed
EP-2451858-B1 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LTD (GB) 2020-10-28 EP disclosed
EP-3215564-B1 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS ARKEMA INC (US) 2020-09-30 EP disclosed
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof KETONEX LIMITED (GB) 2019-10-22 US disclosed
US-10377846-B2 Processes for increasing density of polymer flakes and powders ARKEMA INC. (US) 2019-08-13 US disclosed
US-20170306075-A1 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS ARKEMA INC. 2017-10-26 US disclosed
EP-3215564-A2 PROCESSES FOR INCREASING DENSITY OF POLYMER FLAKES AND POWDERS Arkema, Inc. (US) 2017-09-13 EP disclosed
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF OXFORD PERFORMANCE MATERIALS, INC 2017-09-07 US disclosed
EP-3191442-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF Ketonex Limited (GB) 2017-07-19 EP disclosed
WO-2016038370-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF KETONEX LIMITED (GB) 2016-03-17 WO disclosed
US-9023468-B2 Method for preparing poly (ether ketone ketones) KETONEX LIMITED (GB) 2015-05-05 US disclosed
US-20120263953-A1 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LIMITED (GB) 2012-10-18 US disclosed
EP-2451858-A2 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) Ketonex Limited (GB) 2012-05-16 EP disclosed
WO-2011004164-A2 METHOD FOR PREPARING POLY (ETHER KETONE KETONES) KETONEX LIMITED (GB) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450408-B2 Method for making polyarylaliphaticetherketone polymers and copolymers thereof DAO, DCXR, LOX MAPT 4080/4885MEN1 4480/4885ALDH1A1 815/4885
US-20170253696-A1 METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF COASY, FRK, PBK MAPT 3631/4885MEN1 4316/4885ALDH1A1 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.