SCHEMBL514956

SCHEMBL514956

CCCCC=C[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514955 1.00
SCHEMBL7357055 0.95 TRPV1 (0.43)
SCHEMBL7285359 0.95 FAAH (0.43)
SCHEMBL7357057 0.95 TRPV1 (0.43)
SCHEMBL7285356 0.95 FAAH (0.43)
SCHEMBL1535636 0.92
SCHEMBL1769043 0.92
SCHEMBL2163660 0.90 FAAH (0.54)
SCHEMBL910497 0.90 FAAH (0.54)
SCHEMBL1240474 0.90 FAAH (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1259948-A 6,7-disubstituted-4-aminopyrido [2,3-D] pyrimidine compounds ABBOTT LAB (US) 2000-07-12 CN claimed
WO-2024029475-A1 WAVELENGTH CONVERSION FILM FORMING COMPOSITION 日産化学株式会社 2024-02-08 WO disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-11753385-B2 Method for producing kakeromycin and derivatives thereof OP BIO FACTORY CO., LTD. (JP) 2023-09-12 US disclosed
CN-115160248-A Method for producing Kakeromycin and derivatives thereof 海洋规划生物工厂株式会社 2022-10-11 CN disclosed
CN-114874131-A Method for producing Kakeromycin and derivatives thereof 海洋规划生物工厂株式会社 2022-08-09 CN disclosed
CN-114835596-A Method for producing Kakeromycin and derivatives thereof 海洋规划生物工厂株式会社 2022-08-02 CN disclosed
US-20220024883-A1 METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF OP BIO FACTORY CO., LTD. (JP) 2022-01-27 US disclosed
EP-3263572-B1 METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF SEED RES INSTITUTE CO LTD (JP) 2021-12-15 EP disclosed
US-11155526-B2 Method for producing kakeromycin and derivatives thereof OP BIO FACTORY CO., LTD. (JP) 2021-10-26 US disclosed
WO-2000028330-A1 METHOD FOR SELECTING CATALYTIC ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
WO-2000023577-A1 METHOD FOR PRODUCING CHIRAL CARBOXYLIC ACIDS FROM NITRILES WITH THE ASSISTANCE OF A NITRILASE OR MICROORGANISMS WHICH CONTAIN A GENE FOR THE NITRILASE BASF AKTIENGESELLSCHAFT (DE) 2000-04-27 WO disclosed
EP-0829479-A1 Heterocyclic compounds and their use as angiotensin II antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-18 EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
US-5500427-A ANGIOTENSIN II ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-03-19 US disclosed
EP-0588299-A2 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-03-23 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed