Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683716 | 0.91 | KDR (0.56) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL5149857 | 0.91 | KDR (0.56) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL5184123 | 0.88 | PKM (0.53) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL14338677 | 0.82 | EPHX1 (0.62) | KMT2AEPHX1ALDH1A1HTTPOLB | |
| SCHEMBL4683734 | 0.82 | KDR (0.56) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL4787374 | 0.82 | KDR (0.54) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL4786912 | 0.82 | KDR (0.54) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL5149580 | 0.81 | PKM (0.53) | PKMKMT2AALDH1A1 | |
| SCHEMBL4687419 | 0.80 | MEN1 (0.56) | PKMHSD17B10KMT2AEPHX1ALDH1A1 | |
| SCHEMBL4787593 | 0.80 | EPHX1 (0.54) | PKMHSD17B10KMT2AEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |