Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.53 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155469 | 0.92 | BDKRB1 (0.56) | BDKRB1BDKRB2ALDH1A1ATML3MBTL1 | |
| SCHEMBL5155532 | 0.90 | BDKRB1 (0.58) | BDKRB1BDKRB2F2 | |
| SCHEMBL5171173 | 0.89 | CHRM2 (0.51) | BDKRB1BDKRB2F2 | |
| SCHEMBL5151333 | 0.86 | BDKRB1 (0.39) | BDKRB1BDKRB2CA2ALDH1A1ATM | |
| SCHEMBL5151477 | 0.84 | BDKRB1 (0.55) | BDKRB1BDKRB2F2ALDH1A1ATM | |
| SCHEMBL5150949 | 0.84 | BDKRB1 (0.54) | BDKRB1BDKRB2F2ALDH1A1ATM | |
| SCHEMBL5155432 | 0.81 | BDKRB1 (0.62) | BDKRB1BDKRB2F2 | |
| Hydrochloric Acid SCHEMBL5151160 | 0.79 | BDKRB1 (0.48) | BDKRB1F2 | |
| SCHEMBL4697387 | 0.77 | F2 (0.64) | BDKRB1BDKRB2F2 | |
| Hydrochloric Acid SCHEMBL5150900 | 0.77 | BDKRB1 (0.60) | BDKRB1BDKRB2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373233-B1 | DERIVATIVES OF N-(ARYLSULFONYL)BETA-AMINOACIDS COMPRISING A SUBSTITUTED AMINOMETHYL GROUP, THE PREPARATION METHOD THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-05 | — | — | EP | disclosed |
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |