Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5151201 | 0.90 | BDKRB1 (0.43) | BDKRB1BDKRB2 | |
| SCHEMBL5151471 | 0.86 | BDKRB1 (0.53) | BDKRB1CA2ALDH1A1ATML3MBTL1 | |
| SCHEMBL5151340 | 0.85 | LMNA (0.41) | BDKRB1ALDH1A1ATML3MBTL1ACE | |
| SCHEMBL5155469 | 0.78 | BDKRB1 (0.56) | BDKRB1ALDH1A1ATML3MBTL1BDKRB2 | |
| SCHEMBL5155864 | 0.78 | TP53 (0.39) | BDKRB1ALDH1A1ATML3MBTL1BDKRB2 | |
| SCHEMBL5155532 | 0.77 | BDKRB1 (0.58) | BDKRB1BDKRB2 | |
| Hydrochloric Acid SCHEMBL5151207 | 0.76 | BDKRB1 (0.44) | BDKRB1BDKRB2 | |
| SCHEMBL5171173 | 0.76 | CHRM2 (0.51) | BDKRB1BDKRB2 | |
| SCHEMBL5155879 | 0.73 | EEF2K (0.53) | ALDH1A1ATML3MBTL1EEF2K | |
| SCHEMBL5151477 | 0.71 | BDKRB1 (0.55) | BDKRB1ALDH1A1ATML3MBTL1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |