Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CCND1 | P24385 | 4/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.43 |
| ▸ | ITGAL | P20701 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149438 | 0.92 | CDK4 (0.52) | CDK4CCND1ITGB2ICAM1ITGAL | |
| Tryptophanol SCHEMBL5154467 | 0.89 | ITGB2 (0.50) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5152530 | 0.82 | ITGB2 (0.55) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5149376 | 0.81 | CDK4 (0.53) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5149264 | 0.80 | ERAP2 (0.47) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5155616 | 0.80 | ERAP2 (0.47) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5151665 | 0.79 | HPGDS (0.58) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5151298 | 0.78 | POLB (0.47) | ITGB2ICAM1ITGALPOLBMEN1 | |
| Tryptophanol SCHEMBL5155750 | 0.77 | MEN1 (0.48) | CDK4CCND1ITGB2ICAM1ITGAL | |
| SCHEMBL5149272 | 0.77 | ITGB2 (0.50) | ITGB2ICAM1ITGALPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | CDK4 4400/4885CCND1 592/4885ITGB2 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.