Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.57 |
| ▸ | FAP | Q12884 | 6/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | AKT2 | P31751 | 1/20 | 0.53 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.53 |
| ▸ | FPR1 | P21462 | 4/20 | 0.51 |
| ▸ | FPR2 | P25090 | 4/20 | 0.51 |
| ▸ | GRB2 | P62993 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5155558 | 1.00 | DPP4 (0.58) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5230718 | 0.92 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5229026 | 0.92 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10615090 | 0.91 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8390334 | 0.91 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL8647667 | 0.91 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7305245 | 0.91 | DPP4 (0.65) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL10615092 | 0.90 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL8993841 | 0.90 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP | |
| Trifluoroacetic Acid SCHEMBL6824509 | 0.85 | HDAC8 (0.58) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157454-B2 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20040116353-A1 | Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same | SANOFI (FR) | 2004-06-17 | — | — | US | disclosed |