Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094669 | 0.86 | SMN1; SMN2 (0.54) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL3427239 | 0.85 | EPHX2 (0.65) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL515174 | 0.84 | EPHX2 (0.69) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL9070653 | 0.84 | EPHX2 (0.73) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL2092785 | 0.84 | SMN1; SMN2 (0.59) | EPHX2MAPTTRPV1L3MBTL1HPGD | |
| SCHEMBL9379470 | 0.83 | POLB (0.65) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL514840 | 0.83 | EPHX2 (0.63) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL11555827 | 0.83 | EPHX2 (1.00) | EPHX2MAPTTRPV1KMT2AHPGD | |
| SCHEMBL12953077 | 0.83 | EPHX2 (0.67) | EPHX2MAPTTRPV1L3MBTL1KMT2A | |
| SCHEMBL3022084 | 0.82 | EPHX2 (0.71) | EPHX2MAPTTRPV1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704994-A | A kind of improved method synthesizing indoxacarb intermediate chloroformyl [4- (trifluoromethoxy) phenyl] methyl carbamate | 山东华阳农药化工集团有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109535036-A | A kind of synthetic method of indoxacarb intermediate chloroformyl [4- (trifluoromethoxy) phenyl] methyl carbamate | 山东华阳农药化工集团有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-103910653-B | The preparation method of chlorocarbonyl [4-(trifluoromethoxy) phenyl] methyl carbamate | JINGBO AGROCHEMICALS TECHNOLOGY Co.,Ltd. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-104193696-A | Preparation method for novel insecticide indoxacarb | UNIV CHANGZHOU | 2014-12-10 | — | — | CN | claimed |
| US-20240327363-A1 | METHOD OF PREPARING OF ARTHROPODICIDAL OXADIAZINE INTERMEDIATE | ADAMA MAKHTESHIM LTD. (IL) | 2024-10-03 | — | — | US | disclosed |
| EP-4370501-A1 | METHOD OF PREPARING OF ARTHROPODICIDAL OXADIAZINE INTERMEDIATE | ADAMA MAKHTESHIM LTD. (IL) | 2024-05-22 | — | — | EP | disclosed |
| CN-117940402-A | Method for producing arthropodicidal oxadiazine intermediates | 安道麦马克西姆有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117940402-A | Method for producing arthropodicidal oxadiazine intermediates | 安道麦马克西姆有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023286053-A1 | METHOD OF PREPARING OF ARTHROPODICIDAL OXADIAZINE INTERMEDIATE | ADAMA MAKHTESHIM LTD. (IL) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023286053-A1 | METHOD OF PREPARING OF ARTHROPODICIDAL OXADIAZINE INTERMEDIATE | ADAMA MAKHTESHIM LTD. (IL) | 2023-01-19 | — | — | WO | disclosed |
| CN-110511217-B | Catalyst for catalyzing synthesis of indoxacarb key intermediate and application thereof | 京博农化科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-109535036-B | Synthetic method of indoxacarb intermediate methyl chloroformyl [4- (trifluoromethoxy) phenyl ] carbamate | 山东华阳农药化工集团有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-1059901-C | Preparation of arthropodicidal * diazines | DU PONT (US) | 2000-12-27 | — | — | CN | disclosed |
| EP-1048647-A1 | N-Chlorocarbonyl-carbamate derivative and its use in the preparation of arthropodicidal oxadiazines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| US-6080856-A | Preparation of arthropodicidal oxadiazines | E. I. DU PONT NEMOURS AND COMPANY (US) | 2000-06-27 | — | — | US | disclosed |
| US-6018071-A | Preparation of arthropodicidal ozadiazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-01-25 | — | — | US | disclosed |
| US-5869657-A | Preparation of arthropodicidal oxadiazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| CN-1146205-A | Preparation of arthropodicidal oxadiazines | DU PONT (US) | 1997-03-26 | — | — | CN | disclosed |
| EP-0756594-A1 | PREPARATION OF ARTHROPODICIDAL OXADIAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995029171-A1 | PREPARATION OF ARTHROPODICIDAL OXADIAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327363-A1 | METHOD OF PREPARING OF ARTHROPODICIDAL OXADIAZINE INTERMEDIATE | ACVR2B, DDT, ALPG | EPHX2 379/4885MAPT 4140/4885TRPV1 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.