SCHEMBL514840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL515175	0.83	EPHX2 (0.71)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL3427239	0.79	EPHX2 (0.65)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL515174	0.79	EPHX2 (0.69)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL9070653	0.78	EPHX2 (0.73)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL2097993	0.78	RAB9A (0.50)	KMT2AMAPTL3MBTL1ALDH1A1SMN1; SMN2
	SCHEMBL8858784	0.78	KMT2A (0.73)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL8858788	0.78	KMT2A (0.73)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL9379470	0.78	POLB (0.65)	EPHX2KMT2ATRPV1MAPTL3MBTL1
	SCHEMBL11555827	0.78	EPHX2 (1.00)	EPHX2KMT2ATRPV1MAPTHDAC3
	SCHEMBL3022084	0.77	EPHX2 (0.71)	EPHX2KMT2ATRPV1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.