Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944710 | 0.96 | ALDH1A1 (0.57) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5151439 | 0.91 | ALDH1A1 (0.49) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5155333 | 0.90 | ALDH1A1 (0.48) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4762569 | 0.89 | ALDH1A1 (0.55) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3951294 | 0.87 | CYP2C9 (0.49) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3943632 | 0.87 | ALDH1A1 (0.47) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3952555 | 0.87 | ALDH1A1 (0.47) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3943840 | 0.87 | ALDH1A1 (0.47) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4112147 | 0.86 | ALDH1A1 (0.46) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14307300 | 0.86 | ALDH1A1 (0.46) | CYP2C9CYP2C19ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197524-A1 | Fluorenes and carbazoles as ligands of the EP2 receptor | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-08-23 | — | — | US | disclosed |
| WO-2007071456-A1 | FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197524-A1 | Fluorenes and carbazoles as ligands of the EP2 receptor | PTGER2, PTGER1, PTGDR2 | CYP2C9 497/4885CYP2C19 160/4885ALDH1A1 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.