Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FASN | P49327 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144968 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL10530183 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL10950101 | 0.97 | ALDH1A1 (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL15641830 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL18131545 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL6899958 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL15641831 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL9770131 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL10950105 | 0.97 | ALDH1A1 (0.54) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL11144299 | 0.97 | TSHR (0.54) | TSHRALDH1A1FASNFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238814-B2 | Compositions of S-nitrosothiols and methods of use | NITROMED, INC. (US) | 2007-07-03 | — | — | US | disclosed |