SCHEMBL5152250

SCHEMBL5152250

CO[Si](Cl)(Cc1ccccc1)OC.CO[Si](OC)(OC)c1ccc(CCl)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.34
LTA4H P09960 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137014 0.82 CA1 (0.34) TTR
SCHEMBL2202415 0.82 LTA4H (0.39) LTA4HSIGMAR1
SCHEMBL25367782 0.80 TTR (0.36) TTR
SCHEMBL17191690 0.73 CA1 (0.31) TTR
SCHEMBL12567428 0.73 CA1 (0.31) TTR
SCHEMBL18037942 0.72
(Chloromethyl)Benzene SCHEMBL27327539 0.70 TP53 (0.46) TTRLTA4HSIGMAR1
SCHEMBL9633278 0.69 TSHR (0.36) LTA4HSIGMAR1
SCHEMBL733889 0.69 TTR (0.35) TTR
SCHEMBL2954273 0.69 TAAR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1782436-A2 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE Novinium, Inc. (US) 2007-05-09 EP disclosed
EP-1744866-A2 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES Novinium, Inc. (US) 2007-01-24 EP disclosed
WO-2005084321-A2 METHOD FOR TREATING ELECTRICAL CABLE AT SUSTAINED ELEVATED PRESSURE NOVINIUM, INC. (US) 2005-09-15 WO disclosed
WO-2005084322-A2 METHOD FOR SELECTING FORMULATIONS TO TREAT ELECTRICAL CABLES NOVINIUM, INC. (US) 2005-09-15 WO disclosed