⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175725 | 0.76 | MGLL (0.42) | — | |
| SCHEMBL461562 | 0.71 | — | — | |
| SCHEMBL18282001 | 0.71 | — | — | |
| SCHEMBL2922210 | 0.71 | — | — | |
| SCHEMBL2571475 | 0.71 | — | — | |
| SCHEMBL22015479 | 0.67 | MGLL (0.35) | — | |
| SCHEMBL28365068 | 0.67 | MGLL (0.35) | — | |
| SCHEMBL5881151 | 0.65 | MGLL (0.46) | — | |
| SCHEMBL1817414 | 0.65 | MGLL (0.36) | — | |
| SCHEMBL9193351 | 0.65 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139352-A1 | HER2 BINDERS | GE Precision Healthcare LLC | 2024-05-02 | — | — | US | disclosed |
| US-11633507-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| EP-3957332-A1 | RADIOLABELED HER2-BINDING PEPTIDE CONJUGATES | General Electric Company (US) | 2022-02-23 | — | — | EP | disclosed |
| EP-3936155-A1 | RADIOLABELED HER2-BINDING PEPTIDE CONJUGATES | General Electric Company (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210170057-A1 | HER2 BINDERS | GEN ELECTRIC (US) | 2021-06-10 | — | — | US | disclosed |
| US-10894097-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2021-01-19 | — | — | US | disclosed |
| US-20190262481-A1 | HER2 BINDERS | AFFIBODY AB (SE) | 2019-08-29 | — | — | US | disclosed |
| US-10159760-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2018-12-25 | — | — | US | disclosed |
| US-20160199521-A1 | HER2 BINDERS | AFFIBODY AB (SE) | 2016-07-14 | — | — | US | disclosed |
| US-9061080-B2 | HER2 binding peptides labeled with aluminium-[18] fluoride complexed by NOTA | GE HEALTHCARE LIMITED (GB) | 2015-06-23 | — | — | US | disclosed |
| WO-2012096760-A1 | RADIOLABLED HER2 BINDING PEPTIDES | GENERAL ELECTRIC COMPANY (US) | 2012-07-19 | — | — | WO | disclosed |
| US-20120165650-A1 | HER2 BINDERS | GENERAL ELECTRIC COMPANY (US) | 2012-06-28 | — | — | US | disclosed |
| WO-2012087908-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087912-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| US-20120027680-A1 | OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE | THE GENERAL HOSPITAL CORPORATION (US) | 2012-02-02 | — | — | US | disclosed |
| CN-102316903-A | PDGF-RBETA binding agents | GEN ELECTRIC | 2012-01-11 | — | — | CN | disclosed |
| US-8030459-B2 | Oxime conjugates and methods for their formation and use | THE GENERAL HOSPITAL CORPORATION (US) | 2011-10-04 | — | — | US | disclosed |
| US-20060058513-A1 | Oxime conjugates and methods for their formation and use | ENERGY, UNITED STATES DEPARTMENT OF | 2006-03-16 | — | — | US | disclosed |
| EP-1534269-A1 | OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE | THE GENERAL HOSPITAL CORPORATION (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004009082-A1 | OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE | THE GENERAL HOSPITAL CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |