⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841502 | 1.00 | — | — | |
| SCHEMBL45142 | 1.00 | — | — | |
| SCHEMBL18279951 | 1.00 | ALDH1A1 (0.62) | — | |
| Hydroxyl Radical SCHEMBL28244610 | 0.97 | — | — | |
| SCHEMBL28283561 | 0.97 | ALDH1A1 (0.59) | — | |
| Methyl Alcohol SCHEMBL4464000 | 0.94 | — | — | |
| Methoxymethane SCHEMBL6931778 | 0.91 | — | — | |
| Oxirane SCHEMBL27656054 | 0.91 | — | — | |
| Propylene Oxide SCHEMBL3619770 | 0.91 | ALDH1A1 (0.54) | — | |
| SCHEMBL4223417 | 0.89 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105346-B | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-3995495-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2022-05-11 | — | — | EP | disclosed |
| EP-3626717-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2020-03-25 | — | — | EP | disclosed |
| CN-110105346-A | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-106414432-B | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2019-06-14 | — | — | CN | disclosed |
| US-RE47193-E1 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-10087174-B2 | Selectively substituted quinoline compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20180072645-A1 | 1,3-FATTY DIOL COMPOUNDS AND DERIVATIVES THEREOF | REG LIFE SCIENCES LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180030045-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-02-01 | — | — | US | disclosed |
| CN-106414432-A | Optionally substituted quinoline compounds | 卫材R&D管理有限公司 | 2017-02-15 | — | — | CN | disclosed |
| US-20150105370-A1 | SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20140275576-A1 | PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | US | disclosed |
| US-8178525-B2 | FXA inhibitors with cyclic amidoxime or cyclic amidrazone as P4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof | LEGOCHEM BIOSCIENCE LTD. (KR) | 2012-05-15 | — | — | US | disclosed |
| EP-1136061-B1 | Optically active, oxygenated, alicyclic compounds and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-01-03 | — | — | EP | disclosed |
| EP-1136061-B1 | Optically active, oxygenated, alicyclic compounds and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-01-03 | — | — | EP | disclosed |
| US-20010031710-A1 | Optically active, oxygenated, alicyclic compounds and their use as perfuming ingredients | FIRMENICH SA (CH) | 2001-10-18 | — | — | US | disclosed |
| EP-1136061-A2 | Optically active, oxygenated, alicyclic compounds and their use as perfuming ingredients | FIRMENICH SA (CH) | 2001-09-26 | — | — | EP | disclosed |
| US-6054426-A | Optically active aliphatic alcohols and their use as perfuming ingredients | FIRMENICH SA (CH) | 2000-04-25 | — | — | US | disclosed |
| EP-0457022-B1 | Optically active aliphatic alcohols and their application as perfume ingredients | FIRMENICH & CIE (CH) | 1994-08-03 | — | — | EP | disclosed |
| EP-0457022-A1 | Optically active aliphatic alcohols and their application as perfume ingredients | FIRMENICH SA (CH) | 1991-11-21 | — | — | EP | disclosed |