Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31263809 | 1.00 | ACHE (0.61) | ACHEMAPTCYP1A2GAARECQL | |
| SCHEMBL10782553 | 0.87 | ACHE (0.71) | ACHEMAPTGAARECQLKMT2A | |
| SCHEMBL8005518 | 0.86 | GAA (0.50) | ACHEMAPTCYP1A2GAARECQL | |
| SCHEMBL11444965 | 0.85 | ACHE (0.69) | ACHEMAPTGAARECQLKMT2A | |
| SCHEMBL25287220 | 0.84 | KMT2A (0.53) | ACHEMAPTCYP1A2GAARECQL | |
| SCHEMBL6699057 | 0.84 | KMT2A (0.53) | ACHEMAPTCYP1A2GAARECQL | |
| SCHEMBL6298063 | 0.83 | KMT2A (0.50) | ACHEMAPTCYP1A2GAARECQL | |
| SCHEMBL10431488 | 0.82 | KMT2A (0.54) | MAPTCYP1A2GAARECQLKMT2A | |
| SCHEMBL27949963 | 0.82 | GAA (0.50) | ACHEMAPTCYP1A2GAARECQL | |
| Butane SCHEMBL4836967 | 0.82 | KMT2A (0.52) | ACHEMAPTCYP1A2GAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083573-A | Organic ligand and preparation method, quantum dot, quantum dot layer and Light-Emitting Diode | 京东方科技集团股份有限公司 | 2016-11-09 | — | — | CN | claimed |
| CN-119053587-A | 5- [7- (3, 4-Dihydro-1H-isoquinoline-2-carbonyl) -1,2,3,4 tetrahydroisoquinolin-6-yl ] -1H-pyrrole-3-carboxamide derivatives, pharmaceutical compositions containing same and use thereof as pro-apoptotic agents | 法国施维雅药厂 | 2024-11-29 | — | — | CN | disclosed |
| CN-111909108-B | Biphenyl compound and preparation method and medical application thereof | 中国药科大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-115637275-A | Preparation method of (S) -2- (4-bromophenyl) propionic acid | 天津药明康德新药开发有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-115141197-A | 3-aromatic heterocyclic substituted phenyl derivative and preparation method and application thereof | 安徽医科大学 | 2022-10-04 | — | — | CN | disclosed |
| WO-2021036495-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF AS DRUG | 广东药科大学 | 2021-03-04 | — | — | WO | disclosed |
| EP-3697792-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076310-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-04-25 | — | — | WO | disclosed |
| CN-109311838-A | The biosynthesis of cannboid prodrug | 蒂温诺特技术有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-106946682-A | A kind of preparation method of propine acid compounds | 大连理工大学 | 2017-07-14 | — | — | CN | disclosed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5919768-A | COMPOUNDS WHICH INHIBIT BINDING OF SELECTINS TO SIALYL-LEWIS-X AND SIALYL-LEWIS-A CARBOHYDRATES | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998050342-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| EP-0840606-A1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0840606-A4 | — | — | 1998-05-13 | — | — | EP | disclosed |
| CN-1151117-A | Binding of E-selectin, P-selectin or L-selectin to sialyl-Lewis(x) or sialyl-lewis(a) | TAXAS BIOTECHNOLOGY CORP (US) | 1997-06-04 | — | — | CN | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |
| WO-1997001335-A1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |