SCHEMBL5152972

SCHEMBL5152972

O=[N+]([O-])c1conn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL10361835 0.98
SCHEMBL9316416 0.66 MAPT (0.45)
SCHEMBL28917256 0.66
SCHEMBL3293293 0.66 MAPT (0.39)
SCHEMBL3466683 0.62
SCHEMBL3294386 0.57 TSHR (0.46)
SCHEMBL3296075 0.57 ALDH1A1 (0.36)
SCHEMBL486333 0.56
SCHEMBL27318360 0.55
SCHEMBL3293694 0.55 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186441-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2025-06-12 US disclosed
US-12213976-B2 Compounds and methods for treating oxalate-related diseases OXALURX, INC. (US) 2025-02-04 US disclosed
US-20240228448-A1 COMPOSITIONS FOR BINDING SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1P1), IMAGING OF S1P1, AND PROCESSES FOR PREPARATION THEREOF WASHINGTON UNIVERSITY (US) 2024-07-11 US disclosed
US-20230110495-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2023-04-13 US disclosed
US-11504367-B2 Compounds and methods for treating oxalate-related diseases OXALURX, INC. (US) 2022-11-22 US disclosed
WO-2022212769-A1 COMPOSITIONS FOR BINDING SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1P1), IMAGING OF S1P1, AND PROCESSES FOR PREPARATION THEREOF WASHINGTON UNIVERSITY (US) 2022-10-06 WO disclosed
CN-114980886-A Compounds and methods for treating oxalate-related diseases 奥沙鲁克斯公司 2022-08-30 CN disclosed
EP-4017490-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES Oxalurx, Inc. (US) 2022-06-29 EP disclosed
WO-2021035196-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. (US) 2021-02-25 WO disclosed
US-20210052586-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2021-02-25 US disclosed
EP-1451162-A1 SUBSTITUTED DIPHENYL HETEROCYCLES USEFUL FOR TREATING HCV INFECTION Rigel Pharmaceuticals, Inc. (US) 2004-09-01 EP disclosed
US-6759538-B2 PREVENTION INFECTIONS OF HEPATITIS C VIRUS RIGEL PHARMACEUTICALS, INC. 2004-07-06 US disclosed
US-20030165561-A1 Substituted diphenyl heterocycles useful for treating HCV infection MIDCAP FINANCIAL TRUST 2003-09-04 US disclosed
WO-2003040112-A1 SUBSTITUTED DIPHENYL HETEROCYCLES USEFUL FOR TREATING HCV INFECTION RIGEL PHARMACEUTICALS, INC. (US) 2003-05-15 WO disclosed
EP-0747357-B1 Dihydropyridine NPY antagonists: piperidine derivatives BRISTOL MYERS SQUIBB CO (US) 2002-01-09 EP disclosed
US-5635503-A TREATMENT OF EATING DISORDERS, PROMOTING WEIGHT LOSS BRISTOL-MYERS SQUIBB COMPANY (US) 1997-06-03 US disclosed
EP-0747356-A1 Dihydropyridine NPY antagonists: piperazine derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-11 EP disclosed
EP-0747357-A2 Dihydropyridine NPY antagonists: piperidine derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-11 EP disclosed
EP-0747378-A1 Dihydropyridine NPY antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-11 EP disclosed
US-5554621-A Dihydropyridine NPY antagonists: nitrogen heterocyclic derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 1996-09-10 US disclosed