Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766611 | 0.87 | TSHR (0.51) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL7847617 | 0.85 | PKM (0.65) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL29046043 | 0.84 | PKM (0.55) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL20741517 | 0.84 | TSHR (0.61) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL28003672 | 0.84 | DTYMK (0.44) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL12565695 | 0.84 | TPMT (0.51) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL4298104 | 0.83 | PKM (0.54) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL27468828 | 0.83 | PKM (0.54) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL19601397 | 0.82 | TSHR (0.44) | PKMTSHRTPMTAKR1C3AKR1C2 | |
| SCHEMBL10619775 | 0.81 | HPSE (0.50) | PKMTSHRAKR1C3AKR1C2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189739-B2 | Compounds and methods to treat cardiac failure and other disorders | SCIOS, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| EP-1165151-B1 | INDICATORS FOR MONITORING STERILIZATION WITH PLASMA | PATEL GORDHANBHAI N (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1281080-A4 | COLOR CHANGING STEAM STERILIZATION INDICATOR | JP LAB INC (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1080078-B1 | HETEROCYCLIC COMPOUNDS AND METHODS TO TREAT CARDIAC FAILURE AND OTHER DISORDERS | SCIOS INC (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20030211618-A1 | Color changing steam sterilization indicator | JP LABORATORIES, INC. | 2003-11-13 | — | — | US | disclosed |
| US-6589954-B1 | Indoles, benzimidazoles and benztriazoles which are substituted at the 5 or 6 position with a substituent comprising an aromatic moiety linked through a piperazine ring to said indole, benzimidazole or benztriazole are useful | SCIOS, INC. | 2003-07-08 | — | — | US | disclosed |
| EP-1281080-A1 | COLOR CHANGING STEAM STERILIZATION INDICATOR | JP LABORATORIES, INC. (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1165151-A1 | INDICATORS FOR MONITORING STERILIZATION WITH PLASMA | Patel, Gordhanbhai N. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001086289-A1 | COLOR CHANGING STEAM STERILIZATION INDICATOR | JP LABORATORIES, INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-1080078-A1 | HETEROCYCLIC COMPOUNDS AND METHODS TO TREAT CARDIAC FAILURE AND OTHER DISORDERS | SCIOS INC. (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000061200-A1 | INDICATORS FOR MONITORING STERILIZATION WITH PLASMA | PATEL GORDHANBHAI N (US) | 2000-10-19 | — | — | WO | disclosed |
| WO-1999061426-A1 | HETEROCYCLIC COMPOUNDS AND METHODS TO TREAT CARDIAC FAILURE AND OTHER DISORDERS | SCIOS INC. (US) | 1999-12-02 | — | — | WO | disclosed |