⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700990 | 0.77 | — | — | |
| SCHEMBL2614500 | 0.77 | — | — | |
| SCHEMBL23328196 | 0.72 | — | — | |
| SCHEMBL28320492 | 0.72 | — | — | |
| SCHEMBL5153603 | 0.72 | — | — | |
| SCHEMBL4104913 | 0.72 | — | — | |
| SCHEMBL7535294 | 0.72 | — | — | |
| SCHEMBL28814051 | 0.72 | — | — | |
| SCHEMBL27449111 | 0.69 | — | — | |
| SCHEMBL12731724 | 0.69 | KMT2A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| US-6566530-B2 | Preparing 2-chloro-5-chloromethylthiazole by reacting 2-hydroxy-5-hydroxymethylthiazole with a chloride anion source in the presence of an acid. | SYNGENTA CROP PROTECTION, INC. | 2003-05-20 | — | — | US | disclosed |
| EP-1202979-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010852-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-02-15 | — | — | WO | disclosed |