Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153482 | 1.00 | USP2 (0.61) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL6225681 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL15435147 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL27595598 | 0.93 | ALDH1A1 (0.55) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL2878051 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL99276 | 0.93 | ALDH1A1 (0.55) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL6664880 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL10799760 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL19462801 | 0.93 | ALDH1A1 (0.55) | USP2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL258069 | 0.93 | USP2 (0.65) | USP2LMNAALDH1A1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1738803-A1 | Inhibitors of staphylococcus hominis in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-01-03 | — | — | EP | claimed |
| EP-1576946-A1 | Use of inhibitors of gram-positive cocci in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| EP-1430933-A2 | Cosmetic and pharmaceutical compositions comprising steroid sulfatase inhibitors and their use for the reduction of hair loss | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1393518-A2 | ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-03-03 | — | — | EP | claimed |
| WO-2001099376-A2 | ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | claimed |
| EP-1738803-A1 | Inhibitors of staphylococcus hominis in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1576946-A1 | Use of inhibitors of gram-positive cocci in deodorants and antiperspirants | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1430933-A2 | Cosmetic and pharmaceutical compositions comprising steroid sulfatase inhibitors and their use for the reduction of hair loss | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1393518-A2 | ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2001099376-A2 | ARYLSULFATASE-INHIBITORS IN DEODORANTS AND ANTIPERSPIRANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |