⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426579 | 0.80 | — | — | |
| SCHEMBL7852932 | 0.73 | — | — | |
| SCHEMBL7856432 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL3168993 | 0.71 | — | — | |
| SCHEMBL7853579 | 0.71 | — | — | |
| SCHEMBL7854449 | 0.71 | — | — | |
| SCHEMBL26362012 | 0.67 | — | — | |
| SCHEMBL3071574 | 0.64 | TSHR (0.42) | — | |
| SCHEMBL1386440 | 0.64 | — | — | |
| SCHEMBL14964377 | 0.64 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179137-A1 | Screening of anti-viral drugs and pharmaceuticals composition containing thiazolidinone derivatives | RIMONYX PHARMACEUTICALS LTD. (IL) | 2007-08-02 | — | — | US | disclosed |
| EP-1740176-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-INFLAMMATORY QUINAZOLINECARBOXAMIDE DERIVATIVES | Rimonyx Pharmaceuticals Ltd. (IL) | 2007-01-10 | — | — | EP | disclosed |
| WO-2007000771-A2 | FUSED QUINAZOLINONE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2007-01-04 | — | — | WO | disclosed |
| EP-1738170-A2 | SCREENING OF ANTI-VIRAL DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THIAZOLIDINONE DERIVATIVES | Rimonyx Pharmaceuticals Ltd. (IL) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005089068-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-INFLAMMATORY QUINAZOLINECARBOXAMIDE DERIVATIVES | RIMONYX PHARMACEUTICALS LTD. (IL) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005089067-A2 | SCREENING OF ANTI-VIRAL DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THIAZOLIDINONE DERIVATIVES | RIMONYX PHARMACEUTICALS LTD. (IL) | 2005-09-29 | — | — | WO | disclosed |