Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 14/20 | 0.77 |
| ▸ | PLA2G10 | O15496 | 9/20 | 0.71 |
| ▸ | PLA2G2D | Q9UNK4 | 5/20 | 0.71 |
| ▸ | PLA2G2E | Q9NZK7 | 5/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 5/20 | 0.71 |
| ▸ | PLA2G2F | Q9BZM2 | 4/20 | 0.71 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.71 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.71 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.71 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.71 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.71 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153676 | 0.95 | PLA2G2A (0.74) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5150662 | 0.92 | PLA2G2A (0.75) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5152887 | 0.91 | PLA2G2A (0.73) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5153166 | 0.90 | PLA2G2A (0.79) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5154155 | 0.89 | PLA2G2A (0.78) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5155692 | 0.88 | PLA2G2A (0.71) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5150204 | 0.88 | PLA2G2A (0.73) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5153098 | 0.87 | PLA2G2A (0.75) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5157365 | 0.86 | PLA2G2A (0.77) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B | |
| SCHEMBL5153390 | 0.86 | PLA2G2A (0.77) | PLA2G2APLA2G10PLA2G2DPLA2G2EPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202963-B1 | SPLA2 INHIBITORS | LILLY CO ELI (US) | 2007-01-03 | — | — | EP | claimed |