SCHEMBL5154460

SCHEMBL5154460

O=C1CCC(=O)N1C(O)N1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
PKM P14618 1/20 0.36
SLC1A2 P43004 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
KMT2A Q03164 2/20 0.31
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8212689 0.81 ALDH1A1 (0.36) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL1536266 0.77 CHRM2 (0.37) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL432176 0.73 ALDH1A1 (0.44) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL8163728 0.71 ALDH1A1 (0.32) ALDH1A1PKM
SCHEMBL23716973 0.69 ALDH1A1 (0.46) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL7132048 0.69 ALDH1A1 (0.37) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL29164207 0.69 ALDH1A1 (0.32) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL1698550 0.69 SMN1; SMN2 (0.41) ALDH1A1PKMSLC1A2CHRM2CHRM4
SCHEMBL5154455 0.67 ALDH1A1 (0.31) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL10644061 0.67 CHRM2 (0.38) ALDH1A1PKMSLC1A2CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762901-B9 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING CIS BIO INT (FR) 2007-01-17 EP claimed
EP-0637968-B2 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATIDE INC (US) 2006-07-26 EP claimed
EP-1004322-B1 Technetium-99m labeled peptides for thrombus imaging DIATIDE INC (US) 2006-06-14 EP claimed
EP-0684843-B1 TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING OF INFLAMMATION DIATIDE INC (US) 2006-05-10 EP claimed
EP-0762901-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING BERLEX INC (US) 2006-04-19 EP claimed
US-20050002861-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
EP-0775160-B1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATIDE INC (US) 2004-08-18 EP claimed
EP-1437145-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation Schering AG (DE) 2004-07-14 EP claimed
EP-0630265-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION DIATIDE INC (US) 2003-04-16 EP claimed
EP-0804481-B1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATIDE INC (US) 2003-04-16 EP claimed
EP-0644778-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATIDE INC (US) 1997-05-14 EP claimed
US-5620675-A MEDICAL DIAGNOSIS DIATECH, INC. (US) 1997-04-15 US claimed
US-5561220-A POLYPEPTIDE CONTAINING POLYSULFATED GLYCAN DIATECH, INC. (US) 1996-10-01 US claimed
US-5552525-A RADIODIAGNOSTIC REAGENTS USING PEPTIDES FOR DETECTION OF INFECTIONS DIATECH INC. (US) 1996-09-03 US claimed
WO-1995003330-A1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATECH, INC. (US) 1995-02-02 WO claimed
WO-1995000553-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1995-01-05 WO claimed
WO-1994023758-A1 RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING DIATECH, INC. (US) 1994-10-27 WO claimed
WO-1994000489-A2 RADIOACTIVELY-LABELED SOMATOSTANTIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1994-01-06 WO claimed
WO-1993025244-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1993-12-23 WO claimed
WO-1993023085-A1 TECHNETIUM-99m LABELED PEPTIDES FOR THROMBUS IMAGING DIATECH, INC. (US) 1993-11-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050002861-A1 Enhanced scintigraphic imaging agents for imaging of infection and inflammation SIGLEC7, CD209, SIGLEC9 ALDH1A1 4795/4885PKM 2015/4885SLC1A2 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.