Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150276 | 0.85 | MAPT (0.44) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL4004428 | 0.84 | MAPT (0.47) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL4465793 | 0.84 | MAPT (0.47) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL6832842 | 0.83 | MEN1 (0.47) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL4454518 | 0.81 | GPR119 (0.44) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL5148361 | 0.81 | MAPT (0.44) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL13671300 | 0.79 | MAPT (0.48) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL13671244 | 0.78 | MAPT (0.49) | MEN1KMT2ATP53MAPTPOLB | |
| SCHEMBL4459096 | 0.78 | KMT2A (0.45) | MEN1KMT2ATP53MAPTTHRB | |
| SCHEMBL19702760 | 0.77 | MAPT (0.53) | MEN1KMT2AMAPTTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773347-A4 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO INC (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1773347-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006019787-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2006-02-23 | — | — | WO | disclosed |